Description

2-Chloro-5-Fluoro-3,8-Dimethylquinoline is a high-purity, multi-substituted quinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated and alkylated structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the quinoline core for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological processes.
• Catalyst Ligand Development: The nitrogen-containing heterocycle can be modified to create novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-5-Fluoro-3,8-Dimethylquinoline
CAS No.	175204-94-1
Molecular Formula	C11H9ClFN
Molecular Weight	209.65 g/mol
Synonyms	2-Chloro-5-fluoro-3,8-dimethylquinoline; 3,8-Dimethyl-2-chloro-5-fluoroquinoline; Quinoline, 2-chloro-5-fluoro-3,8-dimethyl-; 175204-94-1; 2-Chloro-5-fluoro-3,8-dimethyl-quinoline; 5-Fluoro-2-chloro-3,8-dimethylquinoline
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-3,8-Dimethylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.