Description

Ethyl 4-Hydroxy-6-(Trifluoromethoxy)Quinoline-3-Carboxylate is a high-value, multifunctional heterocyclic building block, distinguished by its trifluoromethoxy and ester functional groups. This compound is essential for research and development in advanced material science and pharmaceutical chemistry, offering a versatile scaffold for creating novel molecules with tailored properties. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for synthesizing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and charge-transport layers, due to its electron-deficient quinoline core.
• Chemical Synthesis: Functions as a versatile synthon for further chemical transformations, including hydrolysis, amidation, and cross-coupling reactions to create diverse chemical libraries.
• Fluorine Chemistry Studies: The trifluoromethoxy group makes it a valuable compound for studying the effects of fluorine substitution on biological activity and material properties.

Basic Information

Product Name	Ethyl 4-Hydroxy-6-(Trifluoromethoxy)Quinoline-3-Carboxylate
CAS No.	175203-85-7
Molecular Formula	C₁₃H₁₀F₃NO₄
Molecular Weight	301.22 g/mol
Synonyms	Ethyl 4-hydroxy-6-(trifluoromethoxy)quinoline-3-carboxylate; 6-(Trifluoromethoxy)-4-hydroxyquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-hydroxy-6-(trifluoromethoxy)-, ethyl ester; 4-Hydroxy-6-trifluoromethoxy-quinoline-3-carboxylic acid ethyl ester; Ethyl 4-hydroxy-6-[(trifluoromethyl)oxy]-3-quinolinecarboxylate; CAS 175203-85-7
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-6-(Trifluoromethoxy)Quinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up activities in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.