Description

5-(Trifluoromethoxy)Indole-2-Carboxylic Acid is a high-value, multi-functional indole derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethoxy-substituted indole core offers significant advantages in modulating the physicochemical and metabolic properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the research of advanced organic electronic materials and functional polymers.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(Trifluoromethoxy)Indole-2-Carboxylic Acid
CAS No.	175203-84-6
Molecular Formula	C10H6F3NO3
Molecular Weight	245.16 g/mol
Synonyms	5-(Trifluoromethoxy)-1H-indole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 5-(trifluoromethoxy)-; 5-Trifluoromethoxyindole-2-carboxylic acid; 2-Carboxy-5-(trifluoromethoxy)indole; 5-(Trifluoromethoxy)indole-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 5-(Trifluoromethoxy)Indole-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.