Description

1-[2-(Trifluoromethyl)Quinol-4-Yl]Piperazine is a high-value, fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a quinoline core modified with a trifluoromethyl group and a piperazine moiety, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for developing novel fluorinated organic materials with specific electronic or optical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring complex fluorinated heterocycles.

Basic Information

Product Name	1-[2-(Trifluoromethyl)Quinol-4-Yl]Piperazine
CAS No.	175203-79-9
Molecular Formula	C14H14F3N3
Molecular Weight	281.28 g/mol
Synonyms	4-(Piperazin-1-yl)-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-(1-piperazinyl)quinoline; 1-[2-(Trifluoromethyl)-4-quinolyl]piperazine; Quinoline, 4-(1-piperazinyl)-2-(trifluoromethyl)-; 175203-79-9; 2-Trifluoromethyl-4-piperazinylquinoline; 4-Piperazinyl-2-trifluoromethylquinoline
EINECS	Contact for details

Quality Control

Every batch of 1-[2-(Trifluoromethyl)Quinol-4-Yl]Piperazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong alkalis and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.