Description

6-(Bromomethyl)-2-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl handle and a stable trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized quinoline-based polymers, ligands, and organic electronic materials.
• Cross-Coupling Reactions: The bromomethyl group acts as an excellent electrophile for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce complex side chains.
• Fluorine Chemistry: A valuable source of the trifluoromethylquinoline scaffold for studying structure-activity relationships (SAR) in medicinal chemistry.
• Ligand and Catalyst Development: Utilized to synthesize novel chelating ligands for metal complexes used in catalysis.

Basic Information

Product Name	6-(Bromomethyl)-2-(Trifluoromethyl)Quinoline
CAS No.	175203-72-2
Molecular Formula	C11H7BrF3N
Molecular Weight	290.08 g/mol
Synonyms	2-(Trifluoromethyl)-6-(bromomethyl)quinoline; 6-Bromomethyl-2-trifluoromethylquinoline; Quinoline, 6-(bromomethyl)-2-(trifluoromethyl)-; 175203-72-2; 2-Trifluoromethyl-6-bromomethylquinoline
EINECS	Contact for details

Quality Control

Our 6-(Bromomethyl)-2-(Trifluoromethyl)Quinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.