Description

6-Nitro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, versatile organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its functionalized quinoline scaffold, which serves as a critical building block for the development of complex, biologically active molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to construct novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or emissive layers in advanced electronic materials due to its conjugated system.
• Coordination Chemistry & Ligand Synthesis: The carboxylic acid ester and nitro groups make it a useful starting material for synthesizing chelating ligands for metal complexes.
• Dye and Pigment Intermediate: Employed in the research and production of specialized quinoline-derived dyes and colorants.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cyclization and functional group transformation reactions.

Basic Information

Product Name	6-Nitro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	175087-43-1
Molecular Formula	C₁₂H₁₀N₂O₅
Molecular Weight	262.22 g/mol
Synonyms	Ethyl 6-Nitro-4-oxo-1,4-dihydroquinoline-3-carboxylate; 6-Nitro-4-hydroxyquinoline-3-carboxylic acid ethyl ester; 4-Hydroxy-6-nitroquinoline-3-carboxylic acid ethyl ester; 1,4-Dihydro-6-nitro-4-oxoquinoline-3-carboxylic acid ethyl ester; Quinoline-3-carboxylic acid, 1,4-dihydro-6-nitro-4-oxo-, ethyl ester; 175087-43-1; Ethyl 1,4-dihydro-6-nitro-4-oxoquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Nitro-4-Oxo-1,4-Dihydro-Quinoline-3-Carboxylic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality ensures the material meets the high standards required for research and cGMP-grade pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.