Description

Chloro{[(1R,2R)-(-)-2-Amino-1,2-diphenylethyl](4-toluenesulfonyl)amido}(mesitylene)ruthenium(II), also known as RuCl[(R,R)-TsDPEN](mesitylene), is a high-purity, chiral ruthenium complex with a minimum ruthenium content of 90%. This compound is a highly valuable asymmetric hydrogenation catalyst, prized for its ability to induce high enantioselectivity in the synthesis of chiral molecules. It is essential for R&D and production chemists in the pharmaceutical and fine chemical industries who require reliable, high-performance catalysts for creating optically pure intermediates and active pharmaceutical ingredients (APIs).

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of functionalized ketones, imines, and olefins.
• Pharmaceutical Intermediate Synthesis: Production of chiral alcohols, amines, and amino acids used in drug development.
• Fine Chemical Manufacturing: Synthesis of high-value, optically active compounds for agrochemicals, flavors, and fragrances.
• Academic and Industrial R&D: A key reagent for methodological development in organic synthesis and catalysis research.
• Process Chemistry: Scaling up enantioselective transformations for commercial production under optimized conditions.

Basic Information

Product Name	Chloro{[(1R,2R)-(-)-2-Amino-1,2-diphenylethyl](4-toluenesulfonyl)amido}(mesitylene)ruthenium(II), Min. 90%
CAS No.	174813-82-2
Molecular Formula	C30H33ClN2O2RuS
Molecular Weight	618.18 g/mol
Synonyms	RuCl[(R,R)-TsDPEN](mesitylene); (R,R)-RuCl(tsdpen)(p-cymene); (1R,2R)-N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Chloro(mesitylene)ruthenium(II); N-(p-Toluenesulfonyl)-1,2-diphenylethylenediamine Ruthenium Complex; (R,R)-TsDPEN Ru Catalyst; Asymmetric Hydrogenation Catalyst RuCl(tsdpen); Chiral Ruthenium Diamine Catalyst; 174813-82-2
EINECS	Contact for details

Quality Control

Every batch of our chiral ruthenium catalyst is produced and tested under strict quality protocols to ensure consistent performance and purity for critical asymmetric synthesis. Our products undergo rigorous quality testing, including assay, chiral purity, and residual solvent analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing lot-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. This material is moisture-sensitive; keep the container tightly sealed in a cool, dry place.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Assay (Ru content)	Min. 90%
Purity (HPLC)	Min. 95%
Chiral Purity	Min. 99% ee
Solubility	Soluble in dichloromethane, toluene, THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.