Description

Cbz-β-Amino-L-Alanine tert-Butyl Ester Hydrochloride is a protected amino acid derivative widely used as a key chiral building block in organic synthesis. This compound is essential for the controlled introduction of the β-amino alanine moiety into peptide chains and complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of peptide-based drugs and bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate a β-amino acid residue, enhancing metabolic stability and conformational diversity.
• Proteomics Research: Serves as a specialized building block for creating custom peptides and probes in biochemical and proteomic studies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new drug candidates with improved pharmacological profiles.
• Bioconjugation: Useful for the chemical modification of proteins and other biomolecules.

Basic Information

Product Name	Cbz-β-Amino-L-Alanine tert-Butyl Ester Hydrochloride
CAS No.	174796-88-4
Molecular Formula	C15H22N2O4 • HCl
Molecular Weight	330.81 g/mol (Free base: 294.35)
Synonyms	N-Cbz-3-Amino-L-alanine tert-Butyl Ester Hydrochloride; (S)-3-((((Benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)propanoic Acid Hydrochloride; Z-β-Amino-L-Ala-OtBu • HCl; Nα-Cbz-Nβ-Boc-L-2,3-diaminopropionic Acid tert-Butyl Ester Hydrochloride; Benzyl N-[(2S)-3-[(tert-butoxy)carbonylamino]-1-ethoxy-1-oxopropan-2-yl]carbamate Hydrochloride; Boc-L-Dap(Cbz)-OtBu HCl; Fmoc/Boc protected amino acid derivative (related series).
EINECS	Contact for details

Quality Control

Our Cbz-β-Amino-L-Alanine tert-Butyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.