Description

1H-Indene-1-Carboxylicacid,2,3-Dihydro-6-Nitro-,(+)-(9Ci) CAS NO 174776-68-2 is a high-purity chiral intermediate featuring a nitro-substituted indane carboxylic acid structure. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly within pharmaceutical research and development. It is primarily sought by fine chemical manufacturers and R&D laboratories engaged in developing new therapeutic agents, agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its nitro and carboxylic acid functional groups for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, nonlinear optical materials, and other functional organic compounds.
• Academic & Industrial R&D: A valuable tool for medicinal chemists and process chemists in exploring new synthetic pathways and optimizing manufacturing processes.

Basic Information

Product Name	1H-Indene-1-Carboxylicacid,2,3-Dihydro-6-Nitro-,(+)-(9Ci)
CAS No.	174776-68-2
Molecular Formula	C10H9NO4
Molecular Weight	207.18 g/mol
Synonyms	(+)-6-Nitro-2,3-dihydro-1H-indene-1-carboxylic acid; (1R)-6-Nitro-2,3-dihydro-1H-indene-1-carboxylic acid; (R)-6-Nitroindane-1-carboxylic acid; 6-Nitro-2,3-dihydro-1H-indene-1-carboxylic acid, (R)-; 174776-68-2; (R)-(+)-6-Nitroindan-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 1H-Indene-1-Carboxylicacid,2,3-Dihydro-6-Nitro-,(+)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure consistency and meet the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.