Description

4-Quinolinecarbonyl Chloride,6-Chloro-2-Phenyl- is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a key building block in the development of complex heterocyclic molecules, particularly within the pharmaceutical sector. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its bioactive quinoline core.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Catalyst Ligand Development: Acts as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Quinolinecarbonyl Chloride,6-Chloro-2-Phenyl-
CAS No.	174636-77-2
Molecular Formula	C₁₆H₉Cl₂NO
Molecular Weight	302.16 g/mol
Synonyms	6-Chloro-2-phenylquinoline-4-carbonyl chloride; 2-Phenyl-6-chloroquinoline-4-carbonyl chloride; 6-Chloro-2-phenyl-4-quinolinecarboxylic acid chloride; (6-Chloro-2-phenylquinolin-4-yl)methanoyl chloride; 4-Carboxy-6-chloro-2-phenylquinoline chloride; 174636-77-2; Quinoline-4-carbonyl chloride, 6-chloro-2-phenyl-
EINECS	Contact for details

Quality Control

Every batch of 4-Quinolinecarbonyl Chloride,6-Chloro-2-Phenyl- is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.