Description

4-Quinolinecarbonyl Chloride,7-Chloro-2-Phenyl- is a high-value, multi-functional chemical intermediate characterized by its reactive carbonyl chloride group and substituted quinoline core. This compound matters for its critical role in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in the development of kinase inhibitors and other biologically active quinoline derivatives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated quinoline structure.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
• Academic Research: Employed in university and institutional laboratories for methodological development and exploring new chemical reactions involving acid chlorides and heterocycles.

Basic Information

Product Name	4-Quinolinecarbonyl Chloride,7-Chloro-2-Phenyl-
CAS No.	174636-74-9
Molecular Formula	C16H9Cl2NO
Molecular Weight	302.15 g/mol
Synonyms	7-Chloro-2-phenylquinoline-4-carbonyl chloride; 2-Phenyl-7-chloroquinoline-4-carbonyl chloride; 7-Chloro-2-phenyl-4-quinolinecarboxylic acid chloride; 4-Carboxy-7-chloro-2-phenylquinoline chloride; (7-Chloro-2-phenylquinolin-4-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Quinolinecarbonyl Chloride,7-Chloro-2-Phenyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.