Description

4-Quinolinecarbonyl Chloride,7-Methoxy-2-Phenyl- CAS NO 174636-64-7 is a high-value, functionalized quinoline derivative that serves as a critical synthetic intermediate. Its core value lies in its reactive acid chloride group, which enables efficient coupling reactions for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the quinoline scaffold's bioactivity.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, or organic electronic materials.
• Chemical Synthesis: Enables amide bond formation and other nucleophilic substitution reactions to create complex heterocyclic compounds in laboratory-scale and pilot-scale synthesis.
• Academic & Contract Research: Essential reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in organic chemistry and chemical biology.

Basic Information

Product Name	4-Quinolinecarbonyl Chloride,7-Methoxy-2-Phenyl-
CAS No.	174636-64-7
Molecular Formula	C17H12ClNO2
Molecular Weight	297.74 g/mol
Synonyms	7-Methoxy-2-phenylquinoline-4-carbonyl chloride; 2-Phenyl-7-methoxyquinoline-4-carbonyl chloride; 4-Carbamoyl-7-methoxy-2-phenylquinoline chloride; 7-Methoxy-2-phenyl-4-quinolinecarboxylic acid chloride; 174636-64-7; 4-Quinolinecarbonyl chloride, 7-methoxy-2-phenyl-
EINECS	Contact for details

Quality Control

Our 4-Quinolinecarbonyl Chloride,7-Methoxy-2-Phenyl- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.