Description

(S)-2-Methylpyrrolidine Hydrochloride CAS NO 174500-74-4 is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key precursor for the synthesis of complex pharmaceutical molecules, particularly those requiring specific stereochemistry for optimal biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Synthesis: Used as a ligand or catalyst component in enantioselective reactions to produce single-isomer compounds with high optical purity.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides where specific stereochemistry influences efficacy.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, and fragrances requiring precise molecular architecture.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-2-Methylpyrrolidine Hydrochloride
CAS No.	174500-74-4
Molecular Formula	C5H12NCl
Molecular Weight	121.61 g/mol
Synonyms	(S)-2-Methylpyrrolidine HCl; (S)-2-Methylpyrrolidine Hydrochloride; (2S)-2-Methylpyrrolidine Hydrochloride; (S)-2-Methyl-1-azacyclopentane Hydrochloride; L-2-Methylpyrrolidine Hydrochloride; (S)-(-)-2-Methylpyrrolidine Hydrochloride; Pyrrolidine, 2-methyl-, hydrochloride, (2S)-; 174500-74-4
EINECS	Contact for details

Quality Control

Our (S)-2-Methylpyrrolidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.