Description

Methyl2,4-Dichloroquinazoline-7-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of quinazoline-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides that leverage the quinazoline scaffold for enhanced efficacy.
• Chemical Synthesis Building Block: Serves as a versatile precursor for further functionalization via nucleophilic substitution reactions at the chlorine atoms or modification of the ester group.
• Material Science Research: Investigated as a monomer or precursor for creating specialty polymers and advanced organic materials with specific electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and methodology development.

Basic Information

Product Name	Methyl2,4-Dichloroquinazoline-7-Carboxylate
CAS No.	174074-89-6
Molecular Formula	C10H6Cl2N2O2
Molecular Weight	257.07 g/mol
Synonyms	Methyl 2,4-dichloro-7-quinazolinecarboxylate; 2,4-Dichloroquinazoline-7-carboxylic acid methyl ester; 7-Quinazolinecarboxylic acid, 2,4-dichloro-, methyl ester; Methyl 2,4-dichloroquinazoline-7-carboxylate; 174074-89-6; Methyl 2,4-dichloro-7-quinolinecarboxylate (common misnomer); 2,4-Dichloro-7-methoxycarbonylquinazoline
EINECS	Contact for details

Quality Control

Our Methyl2,4-Dichloroquinazoline-7-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.