Description

7-Quinazolinecarboxylic Acid, 1,2,3,4-Tetrahydro-2,4-Dioxo-, Methyl Ester is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in the research of kinase inhibitors and other targeted therapeutics. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate within the quinazoline scaffold.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of potential drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products.
• Chemical Biology: Employed as a probe or building block in the study of enzyme mechanisms and biological pathways.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex, functionalized quinazoline derivatives.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	7-Quinazolinecarboxylic Acid, 1,2,3,4-Tetrahydro-2,4-Dioxo-, Methyl Ester
CAS No.	174074-88-5
Molecular Formula	C11H8N2O4
Molecular Weight	232.19 g/mol
Synonyms	1,2,3,4-Tetrahydro-2,4-dioxo-7-quinazolinecarboxylic acid methyl ester; Methyl 1,2,3,4-tetrahydro-2,4-dioxoquinazoline-7-carboxylate; 7-Methoxycarbonyl-1,2,3,4-tetrahydroquinazoline-2,4-dione; 7-(Methoxycarbonyl)-3,4-dihydro-2,4-dioxo-1(2H)-quinazolinecarboxylic acid methyl ester; Quinazoline-7-carboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester
EINECS	Contact for details

Quality Control

Our 7-Quinazolinecarboxylic Acid, 1,2,3,4-Tetrahydro-2,4-Dioxo-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.