Description

6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Amine is a fluorinated tetrahydronaphthalene derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both an amine functionality and strategic fluorine substitutions, enabling precise modulation of biological activity and physicochemical properties. This compound is primarily needed by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, including potential central nervous system (CNS) agents and crop protection chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for CNS disorders, due to its tetrahydronaphthalene core.
• Agrochemical Synthesis: Used in creating advanced pesticide and herbicide molecules where fluorine atoms enhance metabolic stability and bioavailability.
• Chemical Biology Probe Development: Serves as a scaffold for designing fluorescent tags or molecular probes to study enzyme interactions and biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.
• Academic & Contract Research: Employed in universities and CROs for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Amine
CAS No.	173998-65-7
Molecular Formula	C10H11F2N
Molecular Weight	183.20 g/mol
Synonyms	2-Amino-6,8-difluoro-1,2,3,4-tetrahydronaphthalene; 6,8-Difluoro-2-amino-1,2,3,4-tetrahydronaphthalene; 1,2,3,4-Tetrahydronaphthalen-2-amine, 6,8-difluoro-; 6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthylamine; 173998-65-7; 6,8-Difluoro-2-tetralinamine
EINECS	Contact for details

Quality Control

Our 6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This amine derivative may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.