Description

Spiro[Isochroman-1,4'-Piperidin]-3-One Hydrochloride CAS NO 173944-52-0 is a high-purity organic salt featuring a complex spirocyclic structure, making it a valuable synthetic intermediate and building block in advanced chemical synthesis. Its primary value lies in its role as a key precursor for the development of novel pharmaceutical compounds, particularly those targeting central nervous system (CNS) disorders. This compound is essential for research and development chemists, medicinal chemists, and process development scientists working in pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Chemical Synthesis: Serves as a versatile scaffold for constructing complex heterocyclic compounds and spirocyclic libraries.
• Agrochemical Development: Potential intermediate in the research and synthesis of new active ingredients for crop protection.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory organic synthesis and methodology development.
• Process Chemistry: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	Spiro[Isochroman-1,4'-Piperidin]-3-One Hydrochloride
CAS No.	173944-52-0
Molecular Formula	C16H20ClNO2
Molecular Weight	293.79 g/mol
Synonyms	3-Oxospiro[isochromane-1,4'-piperidine] hydrochloride; Spiro(isochroman-1,4'-piperidin)-3-one hydrochloride; 1',2',3',4'-Tetrahydrospiro[isochromene-1,4'-piperidine]-3-one hydrochloride; 3H-Spiro[isobenzofuran-1,4'-piperidine]-3-one hydrochloride; 173944-52-0; Spiro[Isochroman-1,4'-Piperidin]-3-One HCl
EINECS	Contact for details

Quality Control

Our Spiro[Isochroman-1,4'-Piperidin]-3-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with complete batch data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.