Description

Spiro[Isochroman-1,4'-Piperidine] Hydrochloride CAS NO 173943-98-1 is a high-purity organic salt compound featuring a unique spirocyclic molecular architecture. This compound serves as a critical pharmaceutical intermediate and advanced building block in modern synthetic chemistry, enabling the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the synthesis of complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Neurological Research: Used as a core scaffold in medicinal chemistry programs targeting receptors and enzymes within the central nervous system.
• Agrochemical Synthesis: Serves as a building block for developing novel crop protection agents with specific biological activity.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, ligands, and catalysts requiring complex spirocyclic structures.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and heterocyclic chemistry at universities and CROs.

Basic Information

Product Name	Spiro[Isochroman-1,4'-Piperidine] Hydrochloride
CAS No.	173943-98-1
Molecular Formula	C13H17NO·HCl
Molecular Weight	239.74 g/mol
Synonyms	Spiro[isochroman-1,4'-piperidine] hydrochloride; 1',4'-Dihydrospiro[isochromene-1,4'-piperidine] hydrochloride; 1,4-Dihydrospiro[isochromene-1,4'-piperidine] hydrochloride; Spiro(isochroman-1,4'-piperidine) HCl; 173943-98-1; 1,4-Dihydro-1,4'-spiro[2]benzopyran-1,4'-piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our Spiro[Isochroman-1,4'-Piperidine] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.