Description

4-Cyclopentene-1,3-Diol, 4-(1,3-Butadiynyl)-, (1R,3S)- (9Ci) is a specialized chiral diol building block featuring a unique cyclopentene core fused with a butadiynyl substituent. This compound is valued for its rigid, functionalized structure, making it a critical intermediate in the synthesis of complex molecules for pharmaceutical and advanced material research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, asymmetric synthesis, and the development of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated, enantiomerically pure ligands for transition metal catalysis.
• Advanced Material Research: Acts as a monomer or building block for novel polymers and organic semiconductors, leveraging its conjugated diyne system.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products containing functionalized cyclopentene rings.
• Chemical Biology Probes: Utilized to create tagged or modified molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	4-Cyclopentene-1,3-Diol, 4-(1,3-Butadiynyl)-, (1R,3S)- (9Ci)
CAS No.	173933-41-0
Molecular Formula	C9H8O2
Molecular Weight	148.16 g/mol
Synonyms	(1R,3S)-4-(Buta-1,3-diyn-1-yl)cyclopent-4-ene-1,3-diol; (1R,3S)-4-(1,3-Butadiynyl)-4-cyclopentene-1,3-diol; 4-(1,3-Butadiynyl)-4-cyclopentene-1,3-diol, (1R,3S)-rel-; 173933-41-0; (1R,3S)-4-(Buta-1,3-diynyl)cyclopent-4-ene-1,3-diol; 4-Cyclopentene-1,3-diol, 4-(1,3-butadiynyl)-, (1R,3S)-
EINECS	Contact for details

Quality Control

Our production of 4-Cyclopentene-1,3-Diol, 4-(1,3-Butadiynyl)-, (1R,3S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity for research and development. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound may be hygroscopic (moisture-sensitive); handle under an inert atmosphere for critical applications and allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.