Description

(R)-4-[1-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]Benzoic Acid is a chiral benzoic acid derivative of significant importance in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a precursor or resolving agent in catalytic asymmetric reactions to construct complex molecular architectures.
• Peptidomimetics & PROTACs: Incorporation into peptide backbones or as a linker component for the design of proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules.
• Agrochemical Research: Serves as a building block for developing novel, chiral pesticides and herbicides with enhanced activity and selectivity.
• Ligand & Catalyst Development: Utilized in the synthesis of chiral ligands for metal-catalyzed transformations.
• Academic & Process Chemistry: A valuable compound for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	(R)-4-[1-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]Benzoic Acid
CAS No.	173898-15-2
Molecular Formula	C17H17NO4
Molecular Weight	299.32 g/mol
Synonyms	(R)-4-(1-((((Benzyloxy)carbonyl)amino)ethyl)benzoic acid; (R)-N-Cbz-α-methyl-4-aminobenzoic acid; (R)-4-(1-(((Benzyloxy)carbonyl)amino)ethyl)benzoic acid; (R)-N-[(Benzyloxy)carbonyl]-α-methyl-4-aminobenzoic acid; (R)-Cbz-Amp; (R)-4-(1-(Cbz-amino)ethyl)benzoic acid; (R)-N-Cbz-1-(4-carboxyphenyl)ethylamine; (R)-1-(4-Carboxyphenyl)ethyl carbamic acid benzyl ester
EINECS	Contact for details

Quality Control

Our (R)-4-[1-[[(Phenylmethoxy)Carbonyl]Amino]Ethyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.