Description

4-Nitro-1-Trityl-1H-Imidazole is a high-purity, protected imidazole derivative of significant interest in advanced organic synthesis. This compound serves as a crucial synthetic intermediate, particularly valued for its role in the development of nucleoside analogs and other complex heterocyclic systems. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside analogs and antiviral/anticancer drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new therapeutic molecules targeting various enzymes.
• Process Chemistry: Serves as a protected intermediate in multi-step synthetic routes for scale-up and optimization.
• Chemical Biology: Employed in the synthesis of probes and labeled compounds for studying biological mechanisms.
• Academic Research: Utilized in universities and research institutes for developing new synthetic methodologies involving imidazole chemistry.
• Agrochemical Synthesis: Potential intermediate in the development of novel fungicides or herbicides.

Basic Information

Product Name	4-Nitro-1-Trityl-1H-Imidazole
CAS No.	173865-33-3
Molecular Formula	C22H17N3O2
Molecular Weight	355.39 g/mol
Synonyms	1-Trityl-4-nitroimidazole; 4-Nitro-1-tritylimidazole; 1H-Imidazole, 4-nitro-1-(triphenylmethyl)-; 4-Nitro-1-(triphenylmethyl)-1H-imidazole; N-Trityl-4-nitroimidazole; 4-Nitroimidazole, 1-trityl derivative; 173865-33-3; 4-Nitro-1-trityl-1H-imidazole
EINECS	Contact for details

Quality Control

Our 4-Nitro-1-Trityl-1H-Imidazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture sources.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.