Description

1-(Piperidin-4-yl)quinolin-2(1H)-one hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry. This compound matters for its role as a key building block in the synthesis of advanced molecules targeting specific biological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing biochemical probes to study enzyme function and cellular signaling.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	1-(Piperidin-4-yl)quinolin-2(1H)-one hydrochloride
CAS No.	173843-73-7
Molecular Formula	C14H17ClN2O
Molecular Weight	264.75 g/mol
Synonyms	1-(4-Piperidinyl)-2(1H)-quinolinone hydrochloride; 2-Quinolinone, 1-(4-piperidinyl)-, hydrochloride; 1-(Piperidin-4-yl)-1,2-dihydroquinolin-2-one hydrochloride; 1-(Piperidin-4-yl)quinolin-2-one HCl; 4-(2-Oxo-1,2-dihydroquinolin-1-yl)piperidine hydrochloride; 173843-73-7; Quinolin-2(1H)-one, 1-(4-piperidinyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 1-(Piperidin-4-yl)quinolin-2(1H)-one hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.