Description

Cyclohexanecarboxylic Acid, 4-Amino-2-Hydroxy- (9Ci) is a functionalized cyclohexane derivative that serves as a versatile chiral building block and intermediate in advanced organic synthesis. Its value lies in the presence of three distinct functional groups—carboxylic acid, amino, and hydroxy—which allow for selective modifications and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and plant growth regulators that require specific stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and high-value performance materials.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 4-Amino-2-Hydroxy- (9Ci)
CAS No.	173731-97-0
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	4-Amino-2-hydroxycyclohexanecarboxylic acid; 2-Hydroxy-4-aminocyclohexanecarboxylic acid; trans-4-Amino-2-hydroxycyclohexanecarboxylic acid; (1r,2r,4s)-4-Amino-2-hydroxycyclohexanecarboxylic acid; 4-Amino-2-hydroxy-1-cyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 4-amino-2-hydroxy-; A building block for sitagliptin synthesis
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 4-Amino-2-Hydroxy- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.