Description

4-Chloro-2-(Trifluoroacetyl)Aniline Hydrochloride is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both halogen and trifluoroacetyl functional groups, making it a critical building block for the development of complex molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with fluorine-containing motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chloro and trifluoromethyl groups contribute to biological activity.
• Organic Synthesis Building Block: Serves as a versatile reagent for constructing complex heterocyclic compounds and fine chemicals in research and development laboratories.
• Material Science Research: Employed in the development of specialty polymers and advanced materials that require specific fluorine-based properties.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and functional pigments.

Basic Information

Product Name	4-Chloro-2-(Trifluoroacetyl)Aniline Hydrochloride
CAS No.	173676-59-0
Molecular Formula	C8H6ClF3NO • HCl
Molecular Weight	274.50 g/mol
Synonyms	1-(4-Chloro-2-aminophenyl)-2,2,2-trifluoroethanone hydrochloride; 4-Chloro-2-aminobenzotrifluoride hydrochloride; 2-Amino-5-chloro-α,α,α-trifluoroacetophenone hydrochloride; 4-Chloro-2-(trifluoroacetyl)benzenamine hydrochloride; 4-Chloro-α,α,α-trifluoro-o-aminoacetophenone hydrochloride; 2-Trifluoroacetyl-4-chloroaniline hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoroacetyl)Aniline Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.