Description

(2R,3R,5S,6S)-5,6-Bis(Hydroxymethyl)-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxane CAS NO 173371-55-6 is a high-purity, stereochemically defined chiral building block and synthetic intermediate. This compound is valued for its unique dioxane ring structure with multiple functional handles, making it a critical precursor in advanced organic synthesis and pharmaceutical development. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the production of complex molecules, including active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Serves as a versatile building block for constructing stereocenters in natural products and fine chemicals.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides.
• Ligand and Catalyst Development: Acts as a backbone for creating chiral ligands used in metal-catalyzed asymmetric reactions.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and process research.
• Specialty Polymer Chemistry: Potential monomer for creating polymers with specific stereoregularity and functionality.

Basic Information

Item	Detail
Product Name	(2R,3R,5S,6S)-5,6-Bis(Hydroxymethyl)-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxane
CAS No.	173371-55-6
Molecular Formula	C10H20O6
Molecular Weight	236.26 g/mol
Synonyms	1,4-Dioxane-2,3-dimethanol, 2,3-dimethoxy-2,3-dimethyl-, (2R,3R,5S,6S)-; (2R,3R,5S,6S)-2,3-Dimethoxy-2,3-dimethyl-1,4-dioxane-5,6-dimethanol; Chiral Dioxane Dimethanol Derivative; Tetramethyl Substituted Dioxane Diol; (all-R,S)-5,6-Bis(hydroxymethyl)-2,3-dimethoxy-2,3-dimethyl-1,4-dioxane
EINECS	Contact for details

Quality Control

Our (2R,3R,5S,6S)-5,6-Bis(Hydroxymethyl)-2,3-Dimethoxy-2,3-Dimethyl-1,4-Dioxane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.