Description

4-(11-Azidoundecyl-2-Amino)Quinazoline is a specialized bifunctional organic compound featuring a quinazoline core linked to a long-chain alkyl azide. This unique structure makes it a valuable intermediate for click chemistry applications, particularly in bioconjugation and materials science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing targeted probes, drug delivery systems, and functionalized polymers.

Application

• Bioconjugation and Probe Development: The azide group enables efficient, site-specific labeling of biomolecules (proteins, antibodies, oligonucleotides) via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for imaging, diagnostics, and target identification.
• Pharmaceutical Research: Serves as a key synthetic intermediate for constructing novel drug candidates, especially kinase inhibitors, leveraging the quinazoline pharmacophore.
• Polymer and Materials Functionalization: Used to introduce photoactive or bioactive quinazoline motifs into polymers, surfaces, and nanomaterials to create smart, responsive materials.
• Chemical Biology Tool: Acts as a versatile linker or spacer arm in the synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Diagnostic Assay Development: Employed in the design of assay components and sensor platforms that require specific, covalent attachment chemistry.

Basic Information

Product Name	4-(11-Azidoundecyl-2-Amino)Quinazoline
CAS No.	173219-32-4
Molecular Formula	C19H28N6
Molecular Weight	340.47 g/mol
Synonyms	4-(11-Azidoundecylamino)quinazoline; 2-Amino-4-(11-azidoundecyl)quinazoline; N-(11-Azidoundecyl)quinazolin-4-amine; 4-(11-Azidoundecyl-2-Amino)Quinazoline; Quinazoline, 4-[(11-azidoundecyl)amino]-; 4-Amino-2-(11-azidoundecyl)quinazoline (isomeric); Azido-PEG11-quinazoline amine
EINECS	Contact for details

Quality Control

Our 4-(11-Azidoundecyl-2-Amino)Quinazoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and should be handled under inert atmosphere when possible to prevent degradation. Keep away from strong acids, bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.