Description

3-o-Benzoyl-n-Acetyl-A-D-Galactosaminyl-1-o-n-(Fmoc)Serine Phenacylester is a sophisticated, protected carbohydrate-amino acid conjugate, specifically designed as a key building block for solid-phase peptide synthesis (SPPS). This compound matters because it provides a chemically stable, selectively deprotectable intermediate essential for the controlled synthesis of complex glycopeptides and glycoproteins. Pharmaceutical researchers and biotech companies developing novel therapeutic peptides, vaccines, and diagnostic agents are the primary users of this high-purity biochemical.

Application

• Glycopeptide Synthesis: A critical building block for the solid-phase synthesis of O-linked glycopeptides, enabling the study of glycosylation's role in protein function.
• Pharmaceutical Research: Used in the development of novel therapeutic agents, including anti-cancer vaccines, antimicrobial peptides, and targeted biologics.
• Bioconjugation: Serves as a precursor for creating well-defined glycoconjugates for drug delivery systems and diagnostic probes.
• Chemical Biology Tools: Employed to synthesize probes for studying carbohydrate-protein interactions, enzyme mechanisms, and cell signaling pathways.
• Process Development: Used in scaling up the production of specific glycopeptide sequences for preclinical and clinical studies.

Basic Information

Product Name	3-o-Benzoyl-n-Acetyl-A-D-Galactosaminyl-1-o-n-(Fmoc)Serine Phenacylester
CAS No.	172939-67-2
Molecular Formula	C41H40N2O12
Molecular Weight	752.77 g/mol
Synonyms	Fmoc-Ser[Ac3-α-D-GalNAc(Bz)]-OPac; N-α-Fmoc-O-(3,4,6-tri-O-acetyl-2-deoxy-2-acetamido-α-D-galactopyranosyl)-L-serine phenacyl ester; Fmoc-Ser(Ac3-α-D-GalNAc(Bz))-OPac; Fmoc-L-Serine, O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-, 2-oxo-2-phenylethyl ester, 9H-fluoren-9-ylmethyl ester; Glycopeptide Building Block; SPPS Building Block; Ac3-α-D-GalNAc(Bz)-FmocSer-OPac
EINECS	Contact for details

Quality Control

Our 3-o-Benzoyl-n-Acetyl-A-D-Galactosaminyl-1-o-n-(Fmoc)Serine Phenacylester is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure consistent quality and reliable performance in sensitive synthetic workflows. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and solvent residues is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive). For long-term stability, store desiccated at -20°C. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation. Store away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.