Description

(R)-6,6'-Dimethyl-1,1'-Bi-2-Naphthol CAS NO 172877-00-8 is a high-value, enantiomerically pure chiral ligand and building block of significant importance in asymmetric synthesis. Its core value lies in its ability to induce high stereoselectivity in catalytic reactions, enabling the production of single-enantiomer compounds critical for advanced materials and pharmaceuticals. This product is essential for research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors who require precise chiral control for developing novel active ingredients and functional materials.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including hydrogenation, oxidation, and C-C bond formation.
• As a resolving agent for the separation of racemic mixtures of other chiral compounds.
• As a key building block for the synthesis of complex natural products and pharmaceutical intermediates.
• In the development of chiral stationary phases for analytical and preparative chromatography.
• For research and development of novel catalysts and materials with specific optical properties.
• In the synthesis of advanced polymers and supramolecular structures where chirality dictates function.

Basic Information

Product Name	(R)-6,6'-Dimethyl-1,1'-Bi-2-Naphthol
CAS No.	172877-00-8
Molecular Formula	C22H16O2
Molecular Weight	312.36 g/mol
Synonyms	(R)-(-)-6,6'-Dimethyl-2,2'-dihydroxy-1,1'-binaphthyl; (R)-(-)-6,6'-Dimethyl-BINOL; (R)-6,6'-Dimethyl-1,1'-bi-2-naphthol; (R)-(-)-6,6'-Dimethyl-1,1'-binaphthyl-2,2'-diol; (R)-DM-BINOL; (R)-6,6'-Dimethyl-BINOL; (R)-(-)-6,6'-Dimethyl-2,2'-dihydroxy-1,1'-binaphthalene; (R)-6,6'-Dimethyl-[1,1'-binaphthalene]-2,2'-diol
EINECS	Contact for details

Quality Control

Our (R)-6,6'-Dimethyl-1,1'-Bi-2-Naphthol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (enantiomeric excess) determination by HPLC, to ensure compliance with stringent specifications. Certificates of Analysis (COA) detailing identity, purity, and specific rotation are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light), and prolonged exposure to air should be minimized to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.