Description

tert-Butyl 6-Iodohexylcarbamate is a versatile bifunctional organic building block featuring a protected amine group and a reactive alkyl iodide moiety. This compound is critical for the controlled synthesis of complex molecules, enabling the precise introduction of functionalized hexyl linkers. It is primarily utilized by researchers and process chemists in the pharmaceutical and advanced materials sectors for applications such as linker synthesis in antibody-drug conjugates (ADCs), peptide modification, and polymer functionalization.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of linker-payload constructs in Antibody-Drug Conjugates (ADCs) and targeted therapeutics.
• Peptide Chemistry: Used for the site-specific modification and functionalization of peptides and proteins via alkylation.
• Polymer Science: Serves as a monomer or functionalization agent for creating specialty polymers with tailored properties.
• Chemical Biology Probes: Enables the synthesis of molecular probes and tags for studying biological systems.
• Material Science: Employed in surface modification and the creation of functionalized nanomaterials.
• Organic Synthesis: A valuable reagent for introducing protected aminohexyl chains into complex molecular architectures.

Basic Information

Product Name	tert-Butyl 6-Iodohexylcarbamate
CAS No.	172846-36-5
Molecular Formula	C11H22INO2
Molecular Weight	327.20 g/mol
Synonyms	6-[(tert-Butoxycarbonyl)amino]hexyl Iodide; N-Boc-6-aminohexyl Iodide; 1-Iodo-6-[(tert-butoxycarbonyl)amino]hexane; Boc-NH-(CH2)6-I; tert-Butyl N-(6-iodohexyl)carbamate; 6-Iodohexylcarbamic Acid tert-Butyl Ester; N-(6-Iodohexyl)carbamic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Iodohexylcarbamate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.