Description

Spiro[Bicyclo[2.2.1]Heptane-7,1-Cyclopropane], 2-(1-Methylethyl)-, (1Alpha,2Alpha,4Alpha)- (9Ci) is a high-purity, structurally complex organic compound featuring a unique spirocyclic framework. This compound matters as a sophisticated chemical intermediate, offering a rigid, three-dimensional scaffold that is valuable for advanced research and development in pharmaceutical chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical space due to its constrained, polycyclic structure.
• Ligand and Catalyst Development: Acts as a precursor or core structure for developing chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides, where its unique geometry can influence biological activity.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in universities and corporate labs exploring new reactions and methodologies.

Basic Information

Product Name	Spiro[Bicyclo[2.2.1]Heptane-7,1-Cyclopropane], 2-(1-Methylethyl)-, (1Alpha,2Alpha,4Alpha)- (9Ci)
CAS No.	172505-18-9
Molecular Formula	C12H20
Molecular Weight	164.29 g/mol
Synonyms	(1α,2α,4α)-2-Isopropylspiro[bicyclo[2.2.1]heptane-7,1'-cyclopropane]; 2-Isopropylspiro[bicyclo[2.2.1]heptane-7,1'-cyclopropane], (1α,2α,4α)-; Spiro[bicyclo[2.2.1]heptane-7,1'-cyclopropane], 2-(1-methylethyl)-, (1α,2α,4α)-; 172505-18-9; 2-Isopropyl-1,4-methano-1H-indene, hexahydro- (related structural analog); NSC 405124 (potential screening identifier); Spiro[cyclopropane-1,7'-norbornane], 2'-isopropyl-, (1'R,2'R,4'S)- (stereochemical descriptor)
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[2.2.1]Heptane-7,1-Cyclopropane], 2-(1-Methylethyl)-, (1Alpha,2Alpha,4Alpha)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards where required for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral GC/HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.