Description

α-D-Arabinofuranose, 2-Deoxy-2-Fluoro- (9Ci) is a fluorinated carbohydrate derivative, specifically a fluorinated arabinofuranose analog. This compound is a crucial building block in medicinal chemistry and biochemical research, valued for its role as a metabolic probe and enzyme inhibitor. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel therapeutics and studying carbohydrate metabolism.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of fluorinated nucleoside analogs and other antiviral or anticancer drug candidates.
• Biochemical Research: Used as a stable, non-hydrolyzable substrate analog to study the mechanisms of glycosidases, glycosyltransferases, and other carbohydrate-processing enzymes.
• Diagnostic Probe Development: Employed in the creation of molecular probes for Positron Emission Tomography (PET) imaging, leveraging the fluorine-18 isotope for radiolabeling.
• Glycobiology Studies: Acts as a tool compound to investigate carbohydrate metabolism, cell signaling pathways, and the role of sugars in disease states.
• Antiviral Agent Synthesis: A precursor in the development of potential antiviral medications that target viral polymerases or other enzymes dependent on sugar metabolism.

Basic Information

Product Name	α-D-Arabinofuranose, 2-Deoxy-2-Fluoro- (9Ci)
CAS No.	172102-39-5
Molecular Formula	C5H9FO4
Molecular Weight	152.12 g/mol
Synonyms	2-Deoxy-2-fluoro-α-D-arabinofuranose; 2-Fluoro-2-deoxy-α-D-arabinofuranose; 2-Fluoroarabinofuranose; α-2-Fluoro-2-deoxy-D-arabinofuranose; 2-F-ara; 2-Fluoro-D-arabinose; (2R,3S,4R,5R)-2-Fluorotetrahydro-2H-pyran-3,4,5-triol
EINECS	Contact for details

Quality Control

Our α-D-Arabinofuranose, 2-Deoxy-2-Fluoro- (9Ci) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.