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(1R,2R)-1,2-Dicyclohexylethane-1,2-Diamine CAS NO 171974-48-4
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CAS No.:171974-48-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(1R,2R)-1,2-Dicyclohexylethane-1,2-Diamine is a high-purity, chiral diamine compound characterized by its rigid, C2-symmetric structure. This configuration is critical for its primary role as a privileged ligand and catalyst in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control in their synthetic processes.
Application
- Asymmetric Catalysis: Serves as a key chiral ligand or precursor for metal complexes (e.g., with Ru, Rh, Ir) used in hydrogenation, transfer hydrogenation, and other enantioselective transformations.
- Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) where the introduction of chiral diamino functionality is required.
- Chiral Resolution Agent: Employed for the separation of enantiomers via diastereomeric salt formation or as a chiral selector in chromatography.
- Polymer & Materials Science: Acts as a monomer or cross-linking agent for synthesizing chiral polymers, resins, and advanced materials with specific optical or mechanical properties.
- Agrochemical Synthesis: Utilized in creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
- Organic Synthesis Reagent: Functions as a chiral base or nucleophile in various carbon-carbon and carbon-heteroatom bond-forming reactions.
Basic Information
| Product Name | (1R,2R)-1,2-Dicyclohexylethane-1,2-Diamine |
| CAS No. | 171974-48-4 |
| Molecular Formula | C14H28N2 |
| Molecular Weight | 224.39 g/mol |
| Synonyms | (1R,2R)-1,2-Diamino-1,2-dicyclohexylethane; (1R,2R)-1,2-Diamino-1,2-bis(cyclohexyl)ethane; (R,R)-1,2-Diamino-1,2-dicyclohexylethane; (R,R)-DACH; (1R,2R)-DACH; (R,R)-1,2-Dicyclohexyl-1,2-ethanediamine; (1R,2R)-1,2-Bis(cyclohexyl)ethane-1,2-diamine; trans-(R,R)-1,2-Diaminocyclohexane derivative |
| EINECS | Contact for details |
Quality Control
Our (1R,2R)-1,2-Dicyclohexylethane-1,2-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity standards suitable for research and catalytic applications. Certificates of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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