Description

2-Thiophenemethanol, 2,5-Dihydro-α-Methyl-, 1,1-Dioxide (9Ci) is a specialized heterocyclic building block featuring a sulfone group, which is pivotal for introducing specific stereochemistry and reactivity into target molecules. This compound matters for its role as a high-value chiral intermediate in the synthesis of complex pharmaceuticals and advanced materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides where the sulfone moiety and specific stereochemistry are crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its unique thiophene-sulfone structure.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of high-value fine chemicals.

Basic Information

Product Name	2-Thiophenemethanol, 2,5-Dihydro-α-Methyl-, 1,1-Dioxide (9Ci)
CAS No.	171917-81-0
Molecular Formula	C6H10O3S
Molecular Weight	162.21 g/mol
Synonyms	2,5-Dihydro-α-methyl-2-thiophenemethanol 1,1-dioxide; (2,5-Dihydro-α-methyl-2-thienyl)methanol S,S-dioxide; 2-(Hydroxymethyl)-2,5-dihydro-α-methylthiophene 1,1-dioxide; Tetrahydro-α-methyl-2-thiophenemethanol 1,1-dioxide; 2,5-Dihydro-2-(hydroxymethyl)-α-methylthiophene 1,1-dioxide
EINECS	Contact for details

Quality Control

Our production of 2-Thiophenemethanol, 2,5-Dihydro-α-Methyl-, 1,1-Dioxide (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.