Description

4-[(3-Bromophenyl)Amino]-6,7-Diethoxyquinazoline is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is of significant commercial importance as a key building block in the synthesis of targeted small-molecule therapeutics, particularly kinase inhibitors. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel oncology and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent and selective kinase inhibitors for cancer research.
• Biochemical Research: Used as a reference standard or a core scaffold in structure-activity relationship (SAR) studies for drug discovery programs.
• Organic Synthesis: Serves as a versatile building block for constructing complex quinazoline-based molecules with potential biological activity.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry projects and the development of new chemical entities.

Basic Information

Product Name	4-[(3-Bromophenyl)Amino]-6,7-Diethoxyquinazoline
CAS No.	171745-13-4
Molecular Formula	C₁₈H₁₈BrN₃O₂
Molecular Weight	388.26 g/mol
Synonyms	4-(3-Bromoanilino)-6,7-diethoxyquinazoline; 6,7-Diethoxy-4-[(3-bromophenyl)amino]quinazoline; N-(3-Bromophenyl)-6,7-diethoxy-4-quinazolinamine; 4-(3-Bromophenylamino)-6,7-diethoxyquinazoline; 171745-13-4; 4-(m-Bromoanilino)-6,7-diethoxyquinazoline
EINECS	Contact for details

Quality Control

Our production of 4-[(3-Bromophenyl)Amino]-6,7-Diethoxyquinazoline adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.