Description

6-((tert-Butoxycarbonylamino)Methyl)Picolinic Acid is a high-purity, protected amino acid derivative featuring a picolinic acid scaffold and a Boc-protected amine. This compound is a critical pharmaceutical intermediate and organic building block used in the synthesis of complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and oncological pathways.
• Peptidomimetic Synthesis: Used to incorporate constrained amino acid analogs into peptide chains to enhance stability and biological activity.
• Ligand and Chelator Development: Serves as a precursor for creating novel picolinic acid-based ligands used in catalysis and metal chelation.
• Agrochemical Research: Intermediate in the development of new herbicides and plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring a protected, bifunctional picolinate derivative.

Basic Information

Product Name	6-((tert-Butoxycarbonylamino)Methyl)Picolinic Acid
CAS No.	171670-07-8
Molecular Formula	C₁₂H₁₆N₂O₄
Molecular Weight	252.27 g/mol
Synonyms	6-[(tert-Butoxycarbonylamino)methyl]pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-; Boc-Amino-methyl-picolinic acid; N-Boc-6-(aminomethyl)picolinic acid; (6-((tert-Butoxycarbonylamino)methyl)pyridin-2-yl)carboxylic acid; 6-(Boc-aminomethyl)picolinic acid; tert-Butyl N-[(6-carboxypyridin-2-yl)methyl]carbamate
EINECS	Contact for details

Quality Control

Our 6-((tert-Butoxycarbonylamino)Methyl)Picolinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for preclinical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.