Description

1,4-Diazabicyclo[2.2.2]octane-2-ethanol (9Ci) is a specialized bicyclic tertiary amine derivative, structurally related to the versatile catalyst DABCO (1,4-diazabicyclo[2.2.2]octane). This compound matters for its unique bifunctional structure, which combines a rigid, sterically hindered amine base with a pendant ethanol group, offering distinct reactivity and coordination properties. It is primarily needed by researchers and process chemists in the pharmaceutical and fine chemical industries for applications in catalysis, as a ligand in organometallic chemistry, and as a building block for advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug molecules, particularly those requiring rigid, nitrogen-containing scaffolds.
• Catalysis & Ligand Chemistry: Acts as a ligand for transition metal catalysts or as an organocatalyst itself, leveraging its sterically hindered tertiary amine site for reactions like Michael additions or polymerization.
• Polymer Science: Utilized as a monomer or chain modifier in the production of specialty polymers, such as polyurethanes or epoxy curing agents, where its structure imparts specific thermal or mechanical properties.
• Advanced Material Synthesis: Employed in the development of metal-organic frameworks (MOFs), dendrimers, or ionic liquids due to its ability to act as a linker or functional group carrier.
• Chemical Research & Development: Used as a model compound or reagent in academic and industrial R&D for exploring new synthetic methodologies and reaction mechanisms.

Basic Information

Product Name	1,4-Diazabicyclo[2.2.2]octane-2-ethanol (9Ci)
CAS No.	171351-27-2
Molecular Formula	C8H16N2O
Molecular Weight	156.23 g/mol
Synonyms	2-(1,4-Diazabicyclo[2.2.2]octan-2-yl)ethanol; DABCO Ethanol Derivative; 1,4-Diazabicyclo[2.2.2]octan-2-ylethanol; 2-Hydroxyethyl-1,4-diazabicyclo[2.2.2]octane; TED (Triethylenediamine ethanol derivative); 2-(DABCO-2-yl)ethanol; 171351-27-2; (2.2.2)-Diazabicyclooctane-2-ethanol
EINECS	Contact for details

Quality Control

Our 1,4-Diazabicyclo[2.2.2]octane-2-ethanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications such as assay, impurity profiles, and physical characteristics. For customers with specific purity requirements (e.g., >98% or higher), custom synthesis and tailored QC protocols are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.