Description

(R)-2-Amino-3-Quinolin-2-Yl-Propionic Acid is a high-purity, non-natural amino acid derivative featuring a quinoline moiety, making it a valuable chiral building block for advanced synthesis. Its primary commercial value lies in its role as a key intermediate in the research and development of novel pharmaceuticals, particularly for targeted therapies. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to incorporate complex, optically active structures into new molecular entities.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) research.
• Peptidomimetics Development: Used to construct novel peptide analogs where the quinoline group can impart specific binding or pharmacokinetic properties.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds or probes to study biological pathways and enzyme interactions.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for enantioselective synthesis.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex organic molecules for advanced material science and agrochemical research.

Basic Information

Product Name	(R)-2-Amino-3-Quinolin-2-Yl-Propionic Acid
CAS No.	170421-67-7
Molecular Formula	C₁₂H₁₂N₂O₂
Molecular Weight	216.24 g/mol
Synonyms	(R)-2-Amino-3-(quinolin-2-yl)propanoic acid; (R)-2-Amino-3-(2-quinolyl)propionic acid; D-2-Amino-3-(2-quinolyl)propionic acid; (R)-2-Quinolin-2-yl-alanine; (R)-β-(2-Quinolyl)-alanine; (2R)-2-Amino-3-(quinolin-2-yl)propanoic acid; UNII-9Q1VU4F0F8; 170421-67-7
EINECS	Contact for details

Quality Control

Every batch of (R)-2-Amino-3-Quinolin-2-Yl-Propionic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) for each lot, which includes chiral purity verification. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.