Description

4-Bromo-3-Methylbenzamide is a high-purity, versatile brominated aromatic amide building block essential for advanced organic synthesis. This compound matters because it provides a reactive halogen site and a stable amide group, enabling precise molecular construction in complex chemical processes. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for transition metal catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where bromine functionality is required for further derivatization.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.
• Academic and R&D Laboratories: Utilized in fundamental research for method development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	4-Bromo-3-Methylbenzamide
CAS No.	170229-98-8
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	3-Methyl-4-bromobenzamide; 4-Bromo-m-toluamide; 4-Bromo-3-methylbenzoic acid amide; Benzamide, 4-bromo-3-methyl-; 170229-98-8; AI3-26032; BRN 2207175; NSC 405124
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Methylbenzamide is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles. Our quality protocols are designed to support compliance with cGMP, ISO 9001, and other relevant regulatory frameworks for fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.