Description

1-Bromo-4-Fluoro-2-Methyl-5-Nitrobenzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine and bromine atoms for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, enabling the rapid assembly of complex biaryl and heteroaryl structures.
• Fluorine Chemistry: The fluorine atom provides a valuable handle for further chemical modifications and is used to study structure-activity relationships (SAR) in medicinal chemistry.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized nitro- and halogen-substituted dyes and pigments.

Basic Information

Product Name	1-Bromo-4-Fluoro-2-Methyl-5-Nitrobenzene
CAS No.	170098-98-3
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.02 g/mol
Synonyms	5-Bromo-2-fluoro-4-methylnitrobenzene; 2-Fluoro-5-bromo-4-methylnitrobenzene; 4-Bromo-1-fluoro-2-methyl-5-nitrobenzene; 1-Bromo-4-fluoro-2-methyl-5-nitro-benzene; 170098-98-3; Benzene, 1-bromo-4-fluoro-2-methyl-5-nitro-; 2-Methyl-5-nitro-1-bromo-4-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-2-Methyl-5-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.