Description

1,5-Dioxaspiro[5.5]Undecane-9-Carboxylic Acid, 3,3-Dimethyl- is a high-purity, functionalized spirocyclic compound that serves as a versatile and valuable building block in advanced organic synthesis. Its unique rigid spirocyclic structure with a carboxylic acid handle makes it a critical intermediate for constructing complex molecules with precise stereochemistry and functionality. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty materials industries seeking to develop novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its spirocyclic core can contribute to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Material Science: Incorporated into specialty polymers to modify thermal properties, rigidity, and degradation profiles for high-performance applications.
• Fragrance and Flavor Chemistry: Utilized as an intermediate for synthesizing complex macrocyclic and spirocyclic musk compounds and other specialty aroma chemicals.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and further functionalization of spiro compounds.

Basic Information

Item	Detail
Product Name	1,5-Dioxaspiro[5.5]Undecane-9-Carboxylic Acid, 3,3-Dimethyl-
CAS No.	169822-66-6
Molecular Formula	C12H20O4
Molecular Weight	228.29 g/mol
Synonyms	3,3-Dimethyl-1,5-dioxaspiro[5.5]undecane-9-carboxylic acid; 9-Carboxy-3,3-dimethyl-1,5-dioxaspiro[5.5]undecane; 3,3-Dimethyl-1,5-dioxaspiro[5.5]undecane-9-carboxylic acid; Spirocyclic ketal acid; Dimethyl dioxaspiro undecane carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 1,5-Dioxaspiro[5.5]Undecane-9-Carboxylic Acid, 3,3-Dimethyl- is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to guarantee it meets your precise R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.