Description

(R)-1-Cyclohexylpyrrolidin-3-Amine Dihydrochloride is a high-purity chiral amine building block and pharmaceutical intermediate. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in the fields of neurology and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Used as a building block for constructing complex molecules with defined stereochemistry in medicinal chemistry.
• Chemical Research: Serves as a reference standard and starting material in academic and industrial research exploring new chemical entities.
• Ligand Precursor: Can be utilized in the development of chiral ligands for catalysis.
• Process Chemistry: Employed in scale-up and optimization studies for the production of enantiopure pharmaceuticals.

Basic Information

Product Name	(R)-1-Cyclohexylpyrrolidin-3-Amine Dihydrochloride
CAS No.	169532-94-9
Molecular Formula	C10H22Cl2N2
Molecular Weight	241.20 g/mol
Synonyms	(3R)-1-Cyclohexyl-3-pyrrolidinamine dihydrochloride; (R)-1-Cyclohexyl-3-aminopyrrolidine dihydrochloride; (R)-3-Amino-1-cyclohexylpyrrolidine dihydrochloride; (R)-1-Cyclohexylpyrrolidin-3-amine hydrochloride (1:2); UNII-7J3Y1J9Q4F; 7J3Y1J9Q4F; (R)-1-Cyclohexyl-3-pyrrolidinamine hydrochloride; (R)-1-Cyclohexyl-3-pyrrolidinamine, dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-Cyclohexylpyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality control protocols to ensure high chemical purity and enantiomeric excess suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.