Description

(S)-1-Cyclohexylpyrrolidin-3-Amine Dihydrochloride is a high-purity chiral amine building block essential for advanced pharmaceutical research and development. This compound matters as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and psychiatric disorders. Pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers need it for creating novel drug candidates and scaling up production processes. Its defined stereochemistry and dihydrochloride salt form ensure consistent reactivity and handling properties for critical synthetic steps.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of novel central nervous system (CNS) active drugs and receptor modulators.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the research and scale-up of new therapeutic agents.
• Asymmetric Synthesis: Utilized as a chiral amine source or auxiliary in stereoselective chemical transformations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Biology Probes: Used in the development of labeled compounds and molecular probes for biological target identification.
• Catalyst Ligand Precursor: Acts as a starting material for the synthesis of chiral ligands used in homogeneous catalysis.

Basic Information

Item	Detail
Product Name	(S)-1-Cyclohexylpyrrolidin-3-Amine Dihydrochloride
CAS No.	169532-93-8
Molecular Formula	C10H22Cl2N2
Molecular Weight	241.20 g/mol
Synonyms	(S)-1-Cyclohexyl-3-aminopyrrolidine dihydrochloride; (3S)-1-Cyclohexylpyrrolidin-3-amine dihydrochloride; (S)-3-Amino-1-cyclohexylpyrrolidine dihydrochloride; (S)-1-Cyclohexyl-3-pyrrolidinamine dihydrochloride; (S)-1-Cyclohexylpyrrolidin-3-ylamine dihydrochloride; (S)-N-Cyclohexyl-3-aminopyrrolidine dihydrochloride; (S)-1-Cyclohexyl-3-aminopyrrolidine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our (S)-1-Cyclohexylpyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.