Description

4(3H)-Quinazolinone, 2-(((4-((2-Methoxyphenyl)Methylene)-5-Oxo-2-Thioxo-1-Imidazolidinyl)Imino)Methyl)-3-Phenyl- is a sophisticated heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and a valuable scaffold in medicinal chemistry research. Its complex molecular architecture, featuring fused quinazolinone and thiohydantoin moieties, makes it a versatile building block for the synthesis of novel bioactive molecules. This high-purity compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for designing and synthesizing novel libraries of compounds for biological screening.
• Kinase Inhibitor Development: The quinazolinone core is a privileged structure in the development of tyrosine kinase and other enzyme inhibitors.
• Anticancer Agent Research: Investigated for the development of new chemotherapeutic agents due to its complex heterocyclic structure.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study biological pathways and protein functions.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring high-purity, complex intermediates.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-(((4-((2-Methoxyphenyl)Methylene)-5-Oxo-2-Thioxo-1-Imidazolidinyl)Imino)Methyl)-3-Phenyl-
CAS No.	169471-15-2
Molecular Formula	C26H21N5O2S
Molecular Weight	467.55 g/mol
Synonyms	2-(((4-((2-Methoxyphenyl)Methylene)-5-Oxo-2-Thioxo-1-Imidazolidinyl)Imino)Methyl)-3-Phenyl-4(3H)-Quinazolinone; 3-Phenyl-2-({[4-[(2-methoxyphenyl)methylidene]-5-oxo-2-sulfanylideneimidazolidin-1-yl]imino}methyl)-4H-quinazolin-4-one; 169471-15-2; Quinazolinone-thiohydantoin conjugate; Advanced pharmaceutical intermediate 169471-15-2
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality protocols are designed to meet the exacting standards required for pharmaceutical R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.