Description

4(3H)-Quinazolinone, 2-(((4-((2-Chlorophenyl)Methylene)-5-Oxo-2-Thioxo -1-Imidazolidinyl)Imino)Methyl)-3-Phenyl- is a sophisticated heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate and a valuable scaffold in medicinal chemistry research. Its complex molecular architecture, featuring quinazolinone and imidazolidinyl-thioxo moieties, makes it a versatile building block for the synthesis of novel bioactive molecules. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition or receptor modulation, given its specific heterocyclic structure.
• Organic Synthesis Building Block: Utilized in advanced organic synthesis for constructing complex nitrogen- and sulfur-containing heterocycles.
• Agrochemical Research: Investigated as an intermediate for developing new active ingredients in crop protection products.

Basic Information

Item	Details
Product Name	4(3H)-Quinazolinone, 2-(((4-((2-Chlorophenyl)Methylene)-5-Oxo-2-Thioxo -1-Imidazolidinyl)Imino)Methyl)-3-Phenyl-
CAS No.	169471-14-1
Molecular Formula	C26H18ClN5O2S
Molecular Weight	500.97 g/mol
Synonyms	2-(((4-((2-Chlorophenyl)Methylene)-5-Oxo-2-Thioxo-1-Imidazolidinyl)Imino)Methyl)-3-Phenyl-4(3H)-Quinazolinone; 3-Phenyl-2-({[4-[(2-chlorophenyl)methylidene]-5-oxo-2-sulfanylideneimidazolidin-1-yl]imino}methyl)-4H-quinazolin-4-one; 169471-14-1; Quinazolinone derivative; Thiohydantoin-quinazolinone conjugate
EINECS	Contact for details

Quality Control

Our production of this high-purity advanced intermediate adheres to stringent quality protocols. Every batch is characterized and tested to ensure identity, purity, and consistency, supporting reliable outcomes in downstream synthesis. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request. Our quality system is designed to meet the exacting standards of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.