Description

(3-Bromophenyl)-(6-Nitroquinazolin-4-Yl)Amine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinazoline core structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of small molecule kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Research: Used as a core scaffold or derivatization point in the development of chemical probes to study enzyme function and signal transduction pathways.
• Medicinal Chemistry: Serves as a versatile precursor for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	(3-Bromophenyl)-(6-Nitroquinazolin-4-Yl)Amine
CAS No.	169205-77-0
Molecular Formula	C14H9BrN4O2
Molecular Weight	345.15 g/mol
Synonyms	4-[(3-Bromophenyl)amino]-6-nitroquinazoline; 6-Nitro-4-((3-bromophenyl)amino)quinazoline; N-(3-Bromophenyl)-6-nitroquinazolin-4-amine; (3-Bromophenyl)-(6-nitro-4-quinazolinyl)amine; 169205-77-0; 4-(3-Bromoanilino)-6-nitroquinazoline; 6-Nitro-4-(3-bromoanilino)quinazoline
EINECS	Contact for details

Quality Control

Our (3-Bromophenyl)-(6-Nitroquinazolin-4-Yl)Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is accompanied by a detailed Certificate of Analysis (COA). We adhere to relevant industry standards for fine chemical and pharmaceutical intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.