Description

3-(Trifluoromethoxy)Hydrocinnamic Acid is a versatile fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoromethoxy-substituted aromatic structure, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, as well as by fine chemical manufacturers producing specialized intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated components for high-performance liquid crystal displays (LCDs).
• Polymer Modification: Incorporated as a monomer or additive to introduce fluorine into polymer backbones, enhancing chemical resistance and thermal stability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, such as Suzuki or Heck reactions, to construct complex fluorinated aromatic systems.
• Material Science Research: Employed in the development of novel organic electronic materials and coatings with specific surface properties.

Basic Information

Product Name	3-(Trifluoromethoxy)Hydrocinnamic Acid
CAS No.	168833-77-0
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	3-[3-(Trifluoromethoxy)phenyl]propanoic acid; 3-(3-Trifluoromethoxyphenyl)propionic Acid; Hydrocinnamic acid, 3-(trifluoromethoxy)-; m-Trifluoromethoxyhydrocinnamic acid; Benzenepropanoic acid, 3-(trifluoromethoxy)-; 3-(3-(Trifluoromethoxy)phenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Hydrocinnamic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.