Description

4-(Aminomethyl)-1-Methyl-Piperidin-4-Ol(Hcl) is a high-purity piperidine derivative and a valuable pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought by researchers and manufacturers in the pharmaceutical and fine chemical industries for creating new active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in the multi-step synthesis of complex APIs requiring the 4-(aminomethyl)piperidin-4-ol moiety.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Bioconjugation & Probe Development: The primary amine functional group enables its use in bioconjugation chemistry for creating diagnostic probes or targeted drug delivery systems.

Basic Information

Product Name	4-(Aminomethyl)-1-Methyl-Piperidin-4-Ol(Hcl)
CAS No.	168818-68-6
Molecular Formula	C8H19ClN2O
Molecular Weight	194.70 g/mol
Synonyms	4-(Aminomethyl)-1-methyl-4-piperidinol hydrochloride; 1-Methyl-4-(aminomethyl)-4-piperidinol hydrochloride; 4-Piperidinol, 4-(aminomethyl)-1-methyl-, hydrochloride; 4-(Aminomethyl)-1-methylpiperidin-4-ol HCl; 4-Hydroxy-1-methyl-4-piperidinemethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-1-Methyl-Piperidin-4-Ol(Hcl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.