Description

2'-Chloro-Biphenyl-3-Carboxylic Acid is a versatile biphenyl carboxylic acid derivative, distinguished by its chloro substituent which imparts specific reactivity and physical properties. This compound is a critical high-purity intermediate for advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory and research laboratories.

Basic Information

Product Name	2'-Chloro-Biphenyl-3-Carboxylic Acid
CAS No.	168619-03-2
Molecular Formula	C13H9ClO2
Molecular Weight	232.66 g/mol
Synonyms	3-Biphenylcarboxylic acid, 2'-chloro-; 2'-Chloro[1,1'-biphenyl]-3-carboxylic acid; 2'-Chloro-3-biphenylcarboxylic acid; 2-Chlorobiphenyl-3-carboxylic acid; (2'-Chloro-[1,1'-biphenyl]-3-yl)carboxylic acid; NSC 405124; Biphenyl-3-carboxylic acid, 2'-chloro derivative
EINECS	Contact for details

Quality Control

Our 2'-Chloro-Biphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.