Description

1-(Chloromethyl)-2-(Methylsulfonyl)Benzene is a versatile and high-value aromatic building block containing both a reactive chloromethyl group and a methylsulfonyl moiety. This bifunctional nature makes it a critical intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced polymers and functional organic materials with specific electronic or structural properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-(Chloromethyl)-2-(Methylsulfonyl)Benzene
CAS No.	168551-51-7
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	2-(Chloromethyl)phenyl Methyl Sulfone; α-Chloro-o-tolyl Methyl Sulfone; 1-Chloromethyl-2-methylsulfonylbenzene; 2-Methylsulfonylbenzyl Chloride; (2-Methylsulfonylphenyl)methyl Chloride; o-(Chloromethyl)phenyl Methyl Sulfone; Benzene, 1-(chloromethyl)-2-(methylsulfonyl)-; 168551-51-7
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-2-(Methylsulfonyl)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For specific project requirements, we can discuss custom purity grades and analytical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.