Description

(S)-(+)-Amino-2-Methyl-1-Phenyl-Propan-2-Ol Hcl is a high-purity chiral intermediate and building block of significant importance in advanced organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring specific stereochemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Used in the development of chiral catalysts and ligands for asymmetric hydrogenation and other stereoselective transformations.
• Agrochemical Research: Serves as a key intermediate in the synthesis of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals and flavors & fragrances requiring precise stereocontrol.
• Academic & R&D Laboratories: Utilized in methodological development and discovery chemistry for creating novel chiral molecules and studying structure-activity relationships (SAR).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical and chemical analysis.

Basic Information

Product Name	(S)-(+)-Amino-2-Methyl-1-Phenyl-Propan-2-Ol Hcl
CAS No.	168297-77-6
Molecular Formula	C10H16ClNO
Molecular Weight	201.69 g/mol
Synonyms	(S)-(+)-2-Amino-2-methyl-1-phenyl-1-propanol hydrochloride; (1S)-2-Amino-2-methyl-1-phenylpropan-1-ol hydrochloride; (S)-2-Amino-2-methyl-1-phenylpropan-1-ol HCl; L-AMP.HCl; (S)-Phenylpropanolamine derivative; (S)-Norephedrine analog; (1S)-1-Phenyl-2-amino-2-methyl-1-propanol hydrochloride; (S)-α,α-Dimethyl-β-hydroxy-phenethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-(+)-Amino-2-Methyl-1-Phenyl-Propan-2-Ol Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-purity research and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.